My top picks for your excellent HFT  trading system: Deltix, open source Tradelink, X_Trader, and recent Matlab updates!

This came up during a conversation with someone through Linked In”:

I have whittled everything down to Tradelink as it is free. For commercial, I would most likely go with a Deltix if one can afford it. With the latest additions of Matlab 2013, this brings in another potential option now as well. You can also execute trades from Matlab through X_Trader but that appears to be all the current options I would go with. Hope this helps.

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