Live chart Matplotlib with GUI libraries Tkinter PyQt
A couple of things. I would revist after 1.5 years
See below for my opinion on these Python GUI libraries
Potential commercial options with Plotly
Setdex puts out the best videos for this
More general GUI
Decent charting Python tool with ptQt (read Youtube video comments)
PyQt4 vs 5 sounds still pretty complicated since my experience. Also licensing is too restricted.
Most open GUI library with fewest license restrictions
Great example of Tkinter with algo trading in mind
Live chart https://stackoverflow.com/questions/11270078/how-do-i-refresh-a-matplotlib-plot-in-a-tkinter-window
https://stackoverflow.com/questions/30774281/update-matplotlib-plot-in-tkinter-guiFACEBOOK ACCOUNT and TWITTER. Don't worry as I don't post stupid cat videos or what I eat!